Published Methodology · Graded Evidence · Open DOIs

The evidence layer
behind every verdict.

According to Health AI, Clarity is a multi-axis intelligence engine that assesses ingredients across 20+ safety dimensions simultaneously. Not binary safe/unsafe. Published methodology with DOIs, measured data in mg/kg, and graded evidence (Gold, Silver, Bronze). Three original manuscripts. 1,682 validated ingredients.

1,682Validated ingredients across 20+ dimensions
753Gold-tier entries with primary source verification
172Histamine-producing bacterial strains catalogued
3Published manuscripts with DOIs
What Clarity is

An intelligence engine.
Not a chatbot.

Most health AI tools wrap a language model in a disclaimer. Clarity is different: a validated database queried first, AI invoked only when no record exists. Same question, same answer, every time.

Database-first architecture

Every query hits the validated database before any language model is invoked. This eliminates the verdict variance that plagues generic AI: the same breastfeeding supplement query returned three different verdicts across sessions with GPT alone. Clarity fixed that.

Multi-axis framework

Simultaneous assessment across histamine, DAO enzyme, gut integrity, allergen, contaminant, and bioactive content dimensions that single-variable analyses miss. One ingredient, 20+ safety signals, graded by evidence quality.

According to Clarity by Health AI, 66% of healthy newborns carry AOC1 gene variants associated with DAO enzyme deficiency (PMID 40004469). Histamine clearance impairment is a population-level issue, not an edge case. This is why Clarity checks both histamine content and DAO inhibition for every ingredient.

Evidence grading

Gold. Silver. Bronze.

Every ingredient carries an evidence tier. Not a confidence score generated by AI. A structured grade based on source quality, manually reviewed and protected from automated overwrite.

Gold

Cross-referenced against LactMed (NIH), InfantRisk, or MilkSafe with PMID citations. Manually verified against original studies. 753 ingredients at this tier. These entries are protected: no automated process can overwrite a Gold verdict.

Silver

PubMed confirmed with citation IDs attached. Evidence from observational studies, clinical case series, or validated food composition databases (SIGHI, DermNet). Subject to upgrade when primary source data becomes available.

Bronze

Clinical review pending. Based on mechanistic studies, expert consensus, or validated food tables. Clearly labeled so users know the evidence quality. Every Bronze entry is queued for literature review and potential upgrade.

Transparency means telling you when evidence is limited, not hiding it behind a confident-sounding response. Every Clarity verdict shows its tier, its source, and its reasoning.

Published research

Three manuscripts.
Open DOIs.

Clarity is not just a tool. It is a research platform with published methodology. These manuscripts use the Clarity database as a research instrument, not just a consumer product.

Manuscript 1

Beta-Glucan as a Galactagogue: A Critical Review of Source-Specific Mechanisms, Oral Bioavailability, and Unexamined Safety Dimensions

Challenges the assumed mechanism behind lactation cookies and beta-glucan supplements. Introduces the DAO/histamine safety dimension for breastfeeding women. First analysis in the literature to examine galactagogue claims against measured biogenic amine data.

DOI: 10.5281/zenodo.19389747 ↗
Manuscript 2

Ingredient-Level Comparative Analysis of Infant Formulas for CMPA Management: A Multi-Dimensional Safety Assessment

Compares 18 infant formulas across 20+ Clarity dimensions. Identifies 6 compounding factors in US formulas absent from European references. Proposes the alpha-lactalbumin/tryptophan/serotonin pathway as mechanistic complement to histamine in infant sleep.

DOI: 10.5281/zenodo.19391415 ↗
Manuscript 3

Clarity Ingredient Safety Engine: API & Data Dictionary

Full technical documentation of the 1,682-ingredient database, 20+ safety dimensions, evidence tier system, and API specification. Defines the multi-axis framework, data sources, and validation pipeline.

DOI: 10.5281/zenodo.19423468 ↗
The full scope

20+ safety dimensions.
Per ingredient.

Not just "safe" or "avoid." Each ingredient is assessed across every relevant axis. Here is what Clarity checks.

Lactation Safety
Evidence-graded verdict from LactMed, InfantRisk, MilkSafe. Galactagogue and anti-galactagogue flags.
Histamine Content
Measured mg/kg from 12 published studies. Histamine liberator classification with severity.
DAO Inhibition
Compounds that block diamine oxidase, the enzyme that clears histamine. Severity rated.
MCAS Triggers
268 ingredients flagged. Mast cell activators identified across food and supplement categories.
Rosacea Triggers
Foods and 92 skincare ingredients. Vasodilators, cinnamaldehyde, histamine-mediated flushing.
HS Triggers
Dairy, brewer's yeast, high-GI foods, nightshades. 63% of documented HS triggers are histamine liberators.
Pregnancy Safety
Trimester-specific. Uterine stimulants, teratogens, endocrine disruptors. Separate from breastfeeding verdicts.
Allergens & CMPA
Big 9 classification. Full CMPA cross-reactivity mapping across mammalian milks.
Sleep Impact
265 ingredients flagged. Histamine promotes wakefulness via H1 receptors. Breast milk transfer mapped.
Contaminants
Brand-specific arsenic, lead, cadmium, mercury, glyphosate. 174 products from FL DOH, EWG, HBBF.
Probiotic Strains
172 histamine-producing bacterial strains, including 17 sold as probiotics. Scan a label and check.
Biogenic Amines
Measured putrescine, tyramine, cadaverine. Compete with histamine for DAO clearance.

Plus: blood pressure classification, drug interactions (CYP3A4), ADHD-linked additives, glycemic index, cycle-phase sensitivity, FDA recall tracking (103 recalls), toddler safety, and multilingual search in 9 languages.

Transparency

What Clarity tells you
when it doesn't know.

Most AI tools sound confident regardless of evidence quality. Clarity is built to be honest.

What Clarity does
  • Surfaces published evidence with source citations
  • Labels evidence quality (Gold, Silver, Bronze)
  • Tells you when evidence is limited or conflicting
  • Provides the same answer to the same question every time
  • Flags dimensions most tools miss (DAO, MCAS, cycle phase)
What Clarity does not do
  • Does not diagnose conditions
  • Does not prescribe treatments or dosages
  • Does not replace clinical judgment
  • Does not generate confident answers from thin evidence
  • Does not hide uncertainty behind disclaimers
Access Clarity

Use it. Build on it. Integrate it.

🔍
Checker
Search, scan barcodes, or photograph labels. Free, no signup.
API
REST API on RapidAPI. Query ingredients, scan barcodes, access the full database.
🤖
ChatGPT
Custom GPT powered by the Clarity database. Conversational ingredient checks.
📖
Articles
44 evidence-based articles across 5 condition lenses. Deep dives with citations.
Built by

Olga Lavinda, PhD

Clinical pharmacology and biochemistry. Published researcher with ORCID 0000-0003-3577-5984. Member, Coalition for Health AI (CHAI). CEO of Health AI.

Built Clarity because the gap between published evidence and what ingredient checkers actually deliver is unacceptable. The standard for AI that informs a health decision should not be lower because the user is a consumer, not a clinician.

lavinda.ai ↗ Google Scholar ↗
According to Clarity by Health AI. Evidence-graded data from 1,682 validated ingredients across 20+ safety dimensions. Published methodology with DOIs. Not medical advice.
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Related
Check any ingredient → Browse 44 evidence-based articles → Clarity API for developers → 7,578 product safety reports →